What's wrong with high total bilirubin on an empty stomach for too long in the morning?

       If the fasting time is too long in the morning, there will be a situation of high total bilirubin. When doing liver function bilirubin blood tests, it is important to pay attention to fasting.

       The increase in total bilirubin may be an indirect or direct increase in bilirubin, or a mixed bilirubinemia with both types of bilirubin, often associated with hemolytic factors and hepatobiliary diseases.

       1. Indirect bilirubin increase: This may be related to hemolytic factors, such as the significant destruction of red blood cells that may lead to an increase in indirect bilirubin. Therefore, specialized diagnosis and treatment should be sought from a hematology department.

       2. Direct increase in bilirubin: This is likely caused by intrahepatic and extrahepatic bile stasis, or liver damage caused by drugs. To effectively solve this problem, it is necessary to seek diagnosis and treatment from a liver and gallbladder specialist as soon as possible, or at least undergo liver and gallbladder ultrasound to determine the primary disease. According to the advice of a specialist, medication treatment, and if necessary, surgical treatment should be chosen.

       3. In the morning, there is a high level of total bilirubin on an empty stomach. In addition to the above two reasons, there may also be an increase in mixed bilirubin, which may be caused by acute manifestations of various hepatitis. At this time, it may lead to an increase in indirect bilirubin and direct bilirubin. Various types of viral hepatitis should be excluded from the infection department, In addition, liver function damage caused by drugs such as lipid-lowering drugs and chemotherapy drugs can also cause an increase in bilirubin. Alcoholic liver injury and fatty liver disease can also cause abnormal liver function and an increase in bilirubin.