The function of total bile acid determination kit

The total bile acid (TBA) determination kit plays an important role in the medical field, mainly used for quantitative determination of total bile acid content in human serum or plasma in vitro. The following is a detailed explanation of its specific function:

1、 Clinical diagnostic value

Diagnosis of liver disease:

Bile acids are important substances synthesized and secreted by the liver, and their metabolic disorders can reflect the functional status of the liver. When the liver undergoes pathological changes or the biliary system has problems, the metabolism of bile acids will be disrupted, leading to changes in their levels in the blood. Therefore, the total bile acid assay kit has become an important tool for diagnosing liver diseases.

During acute hepatitis, serum TBA levels significantly increase, reaching 10-100 times or even higher than normal levels. If the TBA level in patients with chronic hepatitis exceeds 20 μ mol/L, it may be considered as chronic active hepatitis. When severe liver damage occurs in alcoholic liver disease, serum TBA levels will also significantly increase.

Differential diagnosis:

In addition to liver diseases, diseases such as extrahepatic bile duct obstruction and intrahepatic bile stasis can also cause an increase in TBA. Therefore, the total bile acid assay kit is also of great significance in the differential diagnosis of these diseases.

Observation of therapeutic effect:

During the treatment process, regular monitoring of changes in serum TBA levels can evaluate treatment effectiveness and provide a basis for doctors to adjust treatment plans.

2、 Technical features

High sensitivity and specificity:

The total bile acid determination kit adopts advanced biotechnology and chemical methods, which can accurately detect the total bile acid content in the sample, with high sensitivity and specificity.

Easy to operate:

This reagent kit is easy and fast to operate, does not require complex equipment and technology, and is suitable for use in medical institutions and laboratories at all levels.

Efficiency:

The reagent kit can complete the detection of a large number of samples in a relatively short period of time, greatly improving the efficiency of laboratory work.

Stability and reliability:

The reagent kit has good stability and reliability, which can ensure the accuracy and reproducibility of experimental results.

3、 Application Fields

The total bile acid determination kit is widely used in clinical laboratory, medical research, and drug development fields. It not only helps doctors quickly and accurately diagnose liver and biliary system diseases, providing timely and effective treatment for patients, but also provides important support for medical research and drug development.

In summary, the total bile acid determination kit plays an irreplaceable role in the medical field and is an indispensable and important tool in medical laboratories.